Multifaceted role of keratins in epithelial cell differentiation and transformation

C Dmello, SS Srivastava, R Tiwari, PR Chaudhari… - Journal of …, 2019 - Springer
… The role of keratin phosphorylation in cell transformation/progressionKeratin 8/18 is the first
pair to be expressed during … They found the expression of both K1/K10 and K4/K13 pairs in …

Loss of epidermal MCPIP1 is associated with aggressive squamous cell carcinoma

W Szukala, A Lichawska-Cieslar, R Pietrzycka… - Journal of Experimental …, 2021 - Springer
… the expression of MCPIP1 is related to tumor progression in … , high expression of SCCA2 was
correlated with early onset … of keratin pearls may be correlated with increased expression of …

Loss of DLX3 tumor suppressive function promotes progression of SCC through EGFR–ERBB2 pathway

D Bajpai, S Mehdizadeh, A Uchiyama, Y Inoue… - Oncogene, 2021 - nature.com
… PCNA expression in nucleus and elevated K13 expression in … The alteration of the keratin
pattern in the skin carcinogenesis … For tumor size (papilloma burden), we first took average of …

Utility of keratins as biomarkers for human oral precancer and cancer

M Vaidya, C Dmello, S Mogre - Life, 2022 - mdpi.com
… , the aberrant expression of keratin 17 and non-expression of K13 were … In addition, K8
expression was detected in the early stages of the … K8/18 is the first keratin pair expressed during …

Retinoids and squamous cell differentiation

R Lotan - Retinoids in oncology, 2020 - taylorfrancis.com
… by an increased expression of the K13 keratin (90). In … of the level of the early suprabasal
markers, keratins Kl and K10. In … , the expression of K13 increased after papilloma progress to …

CYLD inhibits the development of skin squamous cell tumors in immunocompetent mice

JP Alameda, VA García-García, S López… - International Journal of …, 2021 - mdpi.com
… immunohistochemical staining for early (keratin K10) … K13—a keratin not expressed in
normal skin and considered a marker of tumor progression when it is aberrantly expressed in skin

Affinity purification of NF1 protein–protein interactors identifies keratins and neurofibromin itself as binding partners

RM Carnes, RA Kesterson, BR Korf, JA Mobley… - Genes, 2019 - mdpi.com
… The keratins especially seem to have the highest rates with K13, 17, … cells, thereby promoting
tumor progression [46]. When … keratin during early development of the human epidermis [48]…

The biology of varicella-zoster virus replication in the skin

C Tommasi, J Breuer - Viruses, 2022 - mdpi.com
… during the distinct stages of differentiation, there are keratins, which are … The earliest
histological evidence of VZV infection from skin … K4 and K13 are also upregulated in differentiated …

Genetically engineered mouse models of esophageal cancer

RA Mahmoudian, M Farshchian… - Experimental cell …, 2021 - Elsevier
… as limited skin expression on the ventral neck of mice models [… The human keratin 4 and 13
(K4 and K13) are expressed in … early stages of tumor development in esophagus of mice [118,…

ɤ-glutamyl hydroxymethyl rhodamine green fluorescence as a prognostic indicator for lung cancer

S Kawashima, T Yoshioka, H Hino, K Kitano… - General Thoracic and …, 2020 - Springer
… These results may be related to the timing of GGT expression, which appears to increase as
… that expression of keratin 13 is an early marker of mouse skin papilloma progression that …